Table 4

Effect of cell cycle arrest on apoptosis in glial cell tumor cells (in vitro)

Cell lineAgentaCell cycle arrestApoptotic index
wt p53
Mutant p53
  • a Toxicity assays were performed at 100 μm TMZ for all lines except for SWB77 and SWB95, which were treated with 200 μm TMZ. All cells were pretreated with BG to neutralize MGMT.