Table 5

Apoptotic indices in glioma xenografts after treatment with TMZ

Xenograft treatedTime after TMZ (h)Apoptotic index: untreatedTMZ
SWB77244a9 ± 4b
4811 ± 6
SWB9524333 ± 5
4864 ± 11
SWB3324622 ± 3
4821 ± 4
SWB4024728 ± 7
4834 ± 11
SWB6124744 ± 8
4861 ± 5
D-5424624 ± 4
4827 ± 5
  • a Apoptotic index in xenografts growing exponentially in athymic mice.

  • b Apoptotic index in xenografts after treatment with 400 mg/m2 TMZ. Mean from three animals ±SD.