Table 1

Cell and colony growth inhibition assays

IC50 represents the mean value of at least three independent experiments ± SD.

AssayIC50 (nm)
IDN 5109PTX
Cell growth inhibition
 DU14517.2 ± 5.719.8 ± 1.2
 PC318.3 ± 3.414.0 ± 5.8
Colony growth inhibition
 DU1458.0 ± 4.69.3 ± 3.5
 PC310.3 ± 4.69.3 ± 3.5