Table 5

Multivariate analysis of disease progression and survival

A. TTP
Factors Associated with Time to ProgressionPRisk ratio (95% CI)
Maintenance BiotherapyP = 0.00080.41 (0.24, 0.69)
Baseline LDH (Reference: LDH > ULN)aP = 0.019 1.86 (1.11, 3.11)
B. Overall survival
Factors associated with overall survival
Maintenance biotherapyP = 0.00010.27 (0.15, 0.49)
No. of metastatic sites (Reference: > 2 sites)P = 0.001 1.64 (1.21, 2.21)
Baseline LDH (Reference: LDH > ULN)P = 0.011 2.25 (1.21, 4.19)
  • a ULN, institutional upper limit of normal.