Table 1

Patient characteristics

Patients entered25
Patients evaluable for toxicitya21
Median age (range), in years72 (54–83)
Performance status (Eastern Cooperative Oncology Group)
 014
 110
 21
Prior treatment for metastatic disease
 Hormonal25
 Radiation10
 Chemotherapy1
Disease sites
 Bone only14
 Soft-tissue only2
 Bone and soft-tissue9
  • a Only patients completing one full course of therapy (4 weeks) were considered evaluable for toxicity (unless DLT observed).