Table 4
Irofulven disposition is linear in nontumor-bearing mice
Dosage (mg/kg)
C
max
(ng/ml)
AUC
0→∞
(ng/ml∗h)
t
1/2β
(min)
3.0
1200
310
34.5
4.6
6500
970
45.5
7.0
9064
1152
54.5