Table 2

Patient characteristics

No. of patients
Weekly schedule (with randomization)Two-weekly schedule (with randomization)Two-weekly schedulea (without randomization)
Total322615
Gender
 Male17136
 Female15139
Age
 Median525155
 Range33–7541–7643–68
PS
 012125
 1141010
 2640
Tumor Stage
 IIIB13111
 IV191514
Previous therapy
 Radiotherapy642
 Chemotherapy000
 Surgery422
 No previous therapy232111
  • a The weekly schedule was abandoned after dose level nine, and subsequent patients were included at the two-weekly schedule without randomization.