Table 2

Patient characteristics, dose of irradiation, efficacy, and toxicity in advanced esophageal carcinoma

Case no.Age/SexSiteLength (cm)StageDoses (Gy)Local responseLocal recurrenceSurvival (mo)UlcerStrictureCause of death
X-rayProtonProton/1fraTotal
1477/MIm8.5III30.653.02.9483.6CRNone19++Respiratory failure caused by lung tuberculosis
1560/MIm6.0III086.53.0986.5CRNone10+Esophageal bleeding
1662/MIm6.0II089.53.0989.5CRNone6++Hepatic failure caused by liver cirrhosis
1750/MIm9.0III085.03.2785.0FailureFailure5Esophageal cancer death (local failure) with esophageal bleeding
1884/MIu15.0III50.433.03.6783.4CRNone32Respiratory failure caused by pneumonia
1951/MIm7.0III50.432.42.9582.8CRYes (44)b132Hepatic failure caused by hepatoma
2073/MIm7.0III50.435.02.9285.4CRYes (8)b18Esophageal cancer death
2185/MIm3.0III075.53.6075.5CRNone11++Respiratory failure caused by pneumonia
2269/MIm7.5III30.654.53.4185.1CRNone7+Cardiac failure caused by ischemic heart disease
2382/FIm4.0III41.439.03.0080.4CRYes (16)b35++Esophageal cancer death
2463/MIu5.0III51.634.02.6185.6CRNone128 (alive)None (alive)
2559/MIm8.0III37.833.03.0070.8CRYes (75)b96Esophageal cancer death
2695/MEi3.0III40.037.03.3677.0CRNone48++Old age
2766/MEi6.0III40.037.03.7077.0CRYes (25)b29+Esophageal cancer death
2867/MEi4.0III48.027.03.0075.0CRYes (27)b49+Esophageal cancer death
2965/MIm5.0III50.025.02.5075.0CRYes (9)b11+Esophageal cancer death
3076/MIm3.0III50.025.02.5075.0CRYes (21)b21+Respiratory failure caused by pneumonia
  • a 1fr, fraction dose; Im, midthoracic esophagus; Ei, lower thoracic esophagus; Ea, abdominal esophagus; Iu, upper thoracic esophagus.

  • b Values in parentheses represent onset of local recurrence (months).