Table 4

Nonhematological toxicity of DHA-paclitaxel (NCI-CTC, version 2.0)

Dose levelNo. of patients/ no. of cyclesNo. of patients with toxicitya
Allergy (infusion reaction/flushing)Skin (pruritus/rash)Constitutional (fatigue/weakness)Gastrointestinal (diarrhea)Gastrointestinal (nausea/vomiting)Neurological (sensory)Pain (arthralgia/myalgia)
Grade 1Grade 2–3Grade 1–2Grade 3Grade 1–2Grade 3Grade 1–2Grade 3Grade 1–2Grade 3Grade 1Grade 2–3Grade 1Grade 2–3
2001/400000000000010
4003/1010002010101010
6606/1810002100300000
88010/2710207131312010
11009/1940317130601010
  • a No grade 4 or 5 toxicities were observed.