Table 3

Association of ET-1 expression with clinicopathological variables in primary breast cancer patients

Clinicopathological variablesET-1 status n positive/total (%)Pa
pT stage
 pT122/68 (32.4)0.036b
 pT226/52 (50.0)
 pT35/11 (45.5)
 pT416/29 (55.2)
Histologic grading
 I–II31/99 (31.3)<0.0001
 III37/60 (61.7)
Lymphovascular invasion
 No48/122 (39.3)NSc; 0.030
 Yes21/38 (55.3)
Distant metastasis
 No42/114 (36.8)0.012
 Yes27/46 (58.7)
  • a χ2 test.

  • b χ2 test for linear trend.

  • c NS, not significant.