Table 5

Relative risk of dying by serum HER2 and YKL-40 level and ER status and one more prognostic variables in a forward stepwise Cox regression model

Prognostic variableNo. of patients with variableRelative risk of dying for
Variable present×High HER2 (>15 μg/liter) n = 32×High YKL-40 (>168 μg/liter) n = 30×ER lacking at diagnosis n = 29
Axillary lymph node involvement at primary diagnosis612.34a2.20b2.64c2.68c
Liver metastases182.33d1.91d2.13e2.09e
More than two metastatic sites134.51c2.05e2.10e2.34b
Age = 50 years561.87d1.95d2.55c2.55a
Symptomatic disease (PS 1 + 2)232.63a1.90d2.57c2.61c
Not obtain a complete remission617.91c f 3.11c f
  • a P < 0.0005.

  • b P < 0.001.

  • c P < 0.0001.

  • d P < 0.01.

  • e P < 0.005.

  • f Not significant.