Table 1

Association between hyperplasia in mucosa adjacent to colon carcinomas and production of metastases in 70 clinical specimens

Mucosal hyperplasiaaNo. of casesNodal metastasis
Positive casesNegative cases
Positive4430 (68%)b14
Negative263 (12%)23b
  • a Hyperplastic change of mucosa was defined morphologically as cryptic columns 1.5 times taller than control mucosa 10 cm from cancer lesion.

  • b P < 0.001 (two-tailed Fisher’s exact test).