Table 2

Statistical analysis of real-time PCR for colon primary and metastatic tumors

Twenty-five colon tumors, 18 primary and 6 metastatic, were studied. Correlation analysis of the real-time PCR data with activity assays was performed (JMP 4.0) The correlation coefficient and P values are tabulated, and the statistically significant values with P ≤ 0.05 are shown in bold.

4-MUA activityCPT-11 hydrolase activityCES1A1 band densityCES2 band densityMiddle band density
CES1A1 PCRr2 = 0.003r2 = 0.008r2 = 0.001r2 = 0.010r2 = 0.035
P = 0.80P = 0.68P = 0.89P = 0.64P = 0.38
CES2 PCR r2 = 0.462 r2 = 0.264 r2 = 0.146 r2 = 0.455 r2 = 0.113
P = 0.0003 P = 0.0103 P = 0.066 P = 0.0003 P = 0.11
CES3 PCRr2 = 0.003r2 = 0.062r2 = 0r2 = 0.004r2 = 0.030
P = 0.79P = 0.24P = 0.97P = 0.76P = 0.42