Pediatric Oncology Series

Clinical Cancer Research is proud to present a special collection of articles from the AACR Childhood Cancer Predisposition Workshop. The initial series of manuscripts was generated by an international cohort of leading pediatric cancer experts in order to provide recommendations for screening surveillance of childhood cancer predisposition syndromes in an effort to facilitate early detection and treatment of pediatric cancers. We hope you enjoy this series of freely available articles and continue to check back for additional relevant content and updated recommendations.

• The future of surveillance in the context of cancer predisposition: through the murky looking glass.
  Malkin D…Brodeur GM. Clinical Cancer Research November 2017.
• Pediatric cancer predisposition and surveillance: an overview, and a tribute to Alfred G. Knudson Jr.
  Brodeur GM…Malkin D. Clinical Cancer Research June 2017.
• Pediatric cancer predisposition imaging: focus on whole-body MRI.
  Greer MLC…States LJ. Clinical Cancer Research June 2017.
• Recommendations for surveillance for children with leukemia-predisposing conditions.
  Porter CC…Nichols KE. Clinical Cancer Research June 2017.
• Recommendations for childhood cancer screening and surveillance in DNA repair disorders
  Walsh MF…Savage SA. Clinical Cancer Research June 2017.
• Clinical management and tumor surveillance recommendations of inherited mismatch repair deficiency in childhood.
  Tabori U…Brugières L. Clinical Cancer Research June 2017.
• Cancer screening recommendations for individuals with Li-Fraumeni syndrome.
  Kratz CP…Malkin D. Clinical Cancer Research June 2017.
• Cancer and central nervous system tumor surveillance in pediatric neurofibromatosis 1.
  Evans DGR…Tabori U. Clinical Cancer Research June 15, 2017.
• Cancer and central nervous system tumor surveillance in pediatric neurofibromatosis 2 and related disorders.
  Evans DGR…Tabori U. Clinical Cancer Research June 15, 2017.
• Cancer surveillance in gorlin syndrome and rhabdoid tumor predisposition syndrome.
  Foulkes WD…Diller L. Clinical Cancer Research June 15, 2017.
• Von hippel–lindau and hereditary pheochromocytoma/paraganglioma syndromes: clinical features, genetics, and surveillance recommendations in childhood.
  Rednam SP…Wasserman JD. Clinical Cancer Research June 15, 2017.
• PTEN, DICER1, FH, and their associated tumor susceptibility syndromes: clinical features, genetics, and surveillance recommendations in childhood.
  Schultz KAP…Foulkes WD. Clinical Cancer Research June 15, 2017.
• Recommendations for cancer surveillance in individuals with rasopathies and other rare genetic conditions with increased cancer risk.
  Villani A…Kratz CP. Clinical Cancer Research June 15, 2017.
• Genetic counselor recommendations for cancer predisposition evaluation and surveillance in the pediatric oncology patient.
  Druker H…Wolfe Schneider K. Clinical Cancer Research July 1, 2017.
• Retinoblastoma and neuroblastoma predisposition and surveillance.
  Kamihara J…Brodeur GM. Clinical Cancer Research July 1, 2017.
• Cancer screening recommendations and clinical management of inherited gastrointestinal cancer syndromes in childhood.
  Achatz MI…Plon SE. Clinical Cancer Research July 1, 2017.
• Surveillance recommendations for children with overgrowth syndromes and predisposition to wilms tumors and hepatoblastoma.
  Kalish JM…Druley TE. Clinical Cancer Research July 1, 2017.
• Multiple endocrine neoplasia and hyperparathyroid-jaw tumor syndromes: clinical features, genetics, and surveillance recommendations in childhood.
  Wasserman JD…Schiffman JD. Clinical Cancer Research July 1, 2017.

Related Articles

• Neuroblastoma patients’ KIR and KIR-ligand genotypes influence clinical outcome for dinutuximab-based immunotherapy: a report from the Children’s Oncology Group.
  Erbe AK…Sondel PM. Clinical Cancer Research January 2018.
• DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies.
  Schultz KAP…Hill DA.Clinical Cancer Research May 2018.